|(1.School of Physical Education，Soochow University，Suzhou 215021，China；
2.Department of Physical Education，Zhanjiang Educational College，Zhanjiang 524037，China；3. Department of Physical Education，Shangqiu Normal College，Shangqiu 476000，China)
Abstract: Metalloproteinases are a large family of enzymes capable of degrading all of the tendon matrix compo-nents, and these are thought to play a major role in the degradation of matrix during tendon remodeling. Some met-alloproteinase enzymes are required for the health of the tendon, and others may be damaging, leading to degenera-tion of the tissue. Now researches indicated mechanical loading and cytokines can regulate MMPs expression and activity, and there is a synergetic or inhibitory effect between them. Exercise leads to tendon remodeling, changing its biomechanical, biochemical and structural properties.
Key words: matrix metalloproteinases；extracellular marix；tendon remodeling；summary