(Department of Physical Education, Zhaoqing Institute, Zhaoqing 526061,China) Abstract: The author carried out a hypoxic exhaust experiment on mice by using a treadmill and a hypoxic chamber, and measured the CK in serum and XOD in skeletal muscles of the mice immediately, on the 1st, 2nd, 4th, and 7th days, after the exercise, so as to study the effect of hypoxia exercise on the mice. The author revealed the following findings: The CK in serum of the mice showed a significant increase immediately, on the 1st and 2nd days, after hypoxic exhaust exercise, while that of the mice in normoxic exercise group began to decrease 4-7 days after the exercise; the CK in serum of the mice in hypoxic exhaust exercise group decreased 4 days after the exercise, yet it increased again on the 7th day; the CK in serum reached its maximum value 7 days after hypoxia exposure; the XOD in skeletal muscles of the mice showed a significant increase immediately, on the 1st 2nd and 4th days, after hypoxic exhaust exercise, and began to decrease 7 days after the exercise; the XOD reached its maximum value 7 days after hypoxia exposure. Hints: The rise of XOD would cause hyperplasia of free radicals, damage of skeletal muscles, and possibly CK leakage, eventually causing the rise of CK after exercise; doubled stimulations of exercise plus hypoxia would intensify oxidative reaction of mice, delaying the repair of skeletal muscles after exercise. Key words: hypoxia; mice; exhaust exercise; CK; XOD |
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