体育学刊

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基因兴奋剂的研究进展
李志朋，徐波，全明辉，薛帅如

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(华东师范大学体育与健康学院，上海200062）
摘要：运用文献综述基因兴奋剂的研究进展，探讨基因兴奋剂的分子机制、基因治疗的基本理论，从基因治疗到基因兴奋剂，基因兴奋剂的操作方法，与有氧耐力相关的基因兴奋剂，如促红细胞生成素基因兴奋剂、血管紧张素转换酶基因兴奋剂；与身体力量相关的基因兴奋剂，如胰岛素样生长因子-1基因兴奋剂、机械生长因子基因兴奋剂；基因兴奋剂的危害、对策，以加深人们对基因兴奋剂的认识，提高人们对基因兴奋剂的警惕。
关键词：基因兴奋剂；基因治疗； EPO基因； ACE基因
中图分类号：G8047文献标识码：A文章编号：1006-7116(2006)06-0056-04

The progress in the study of gene doping
LI Zhipeng, XU Bo, QUAN Minghui, XUE Shuairu

（College of Physical Education and Health,East China Normal University,Shanghai 200062，China）
Abstract:By employing literature approach,the authors reviewed the progress in the study of gene doping,and probed into the following issues in order to intensify people’s knowledge about gene doping and to sharpen people’s vigilance to gene doping: The molecular mechanism of gene doping, basic theories of gene therapy,from gene therapy to gene doping,methods for operating gene doping,aerobic endurance related gene doping such as erythropoietin gene doping and gene doping with angiotensin coverting enzyme,physical strength related gene doping such as gene doping with insulin like growth factor-1 and gene doping with organism growth factor,as well as the hazards of gene doping and corresponding countermeasures.
Key words:gene doping; gene therapy; EPO gene; ACE gene

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