|（1.School of Sports and Leisure，Guangdong Ocean Univesity，Zhanjiang 524088，China；2.Provincial Key Laboratory of Biochemistry，Guangzhou Sport University，Guangzhou 510075，China；3.School of Physical Education，Xinyang Normal University，Xinyang 464000，China）
Abstract: The authors probed into the effect of intermittent hypoxic exercising on the ingestion of nutritional obese SD rats, so as to provide a theoretical criterion for weight reduction through intermittent hypoxic exercising. Hence, the authors established a nutritional obesity model for feeding male SD rats with high fat feed, then let the rats in the intermittent hypoxic exercising group do a 4-week intermittent hypoxic exercise (exercising speed: 20 m/min, (O2): 15.4% in the first two weeks, 14.5% in the last two weeks), and revealed the following findings: as com-pared with the rats in the normoxic calm group, the contents of hypothalamus leptins and leptin receptors of obese SD rats in the normoxic exercising group and intermittent hypoxic exercising group increased (the rats in the nor-moxic exercising group: P<0.05, the rats in the intermittent hypoxic exercising group: P<0.01), and the daily inges-tion of the rats decreased; as compared with the rats in the normoxic exercising group, the contents of hypothalamus leptins and leptin receptors of obese SD rats in the intermittent hypoxic exercising group increased (leptins: P<0.05, leptin receptors: P<0.01). The findings indicated the followings: 1) intermittent hypoxic exercising restrained the appetite of obese rats, reduced their ingestion, and slowed down the increase of their weight; the effect of intermit-tent hypoxic exercising was better than the effect of simple exercising; 2) intermittent hypoxic exercising restraining the appetite of the rats may be related to the restraining of neuropeptide Y as a result of the increase of the contents of hypothalamus leptins and leptin receptors of the rats.
Key words: exercise biochemistry；appetite；intermittent hypoxic exercising；obese rat