|（1.School of Physical Education，Sichuan Normal University，Chengdu 610101，China；2.School of Physical Education，Ludong University，Yantai 264025，China；3.Sichuan Academy of Medical Science，Sichuan Provincial Hospital，Chengdu 610031，China)
Abstract: miRNA regulates the body’s ability to adapt to training stress; its regulating pattern affects aerobic en-durance trainability. Circulating miRNA (c-miRNA) is closely related to miRNA; by analyzing differences in the changing of sport adaptive c-miRNA expression of groups of people at different aerobic endurance trainability lev-els, the authors can acquire the expression spectrum characteristics of c-miRNA sensitively correlative with training. Results: induced by aerobic training stress, the phenotype with high trainability differentially expressed 17 c-miRNAs, 11 of which were up-regulated, 16 of which were down-regulated or steady, its regulating function mainly involved with hypoxia adaptation pathway and the key gene expression of fatty acid β-oxidation metabolism. Hint: aerobic endurance trainability difference is close related to the reactivity of the body’s hypoxia adaptation ability and fatty acid β-oxidation energy supply ability to the induction function of aerobic training. miRNA regulates and in-tegrates the body’s stress adaptive gene expression. C-miRNA differential expression spectrum can be used to evaluate aerobic endurance trainability, and to predict aerobic ability development potential.
Key words: sports biochemistry；aerobic endurance；trainability；c-miRNAs；maximum oxygen uptake；correlation model；sports adaption