| （1.Key Laboratory of Child Development and Learning Science，Ministry of Education，Research Center for Learning Science，Southeast University，Nanjing 210096，China；2.Department of Human Sports Science，Nanjing Institute of Physical Education，Nanjing 210000，China；3.School of Physical Education，Jiangxi Normal University，Nanchang 331000，China；4.Department of Physical Education，Anqing Normal University，Anqing 246011，China) Abstract: In order to probe into the effects of restrained stress on monoamine neurotransmitters and behaviors of mice as well as aerobic exercise intervention effects, the authors selected 80 1-month old C57BL/6 mice, randomly divided them into 4 groups: a control group (Control, n=20), a restrained stress group (Stress, n=20), an exercise group (Ex, n=20) and an exercise + restrained stress group (Stress + Ex, n=20), fed the control group in a calm con-dition, let the restrained stress group suffer restrained stress for 2 weeks, let the exercise group exercise on a tread-mill 2 hours a day, let the exercise + restrained stress group suffer restrained stress and exercise on a treadmill si-multaneously, and revealed the following findings: in the behavior experiment, the mice in the restrained stress group had significantly decreased social behaviors and significantly increased levels of anxiety and depression be-haviors (P<0.05), while exercise intervention could alleviate the effects of restrained stress on these behaviors. Bio-chemical indexes indicated as well that aerobic exercise effectively alleviated retrained stress induced changes of behaviors and monoamine neurotransmitters. Conclusion: restrained stress will cause changes of social communica-tion and emotion related behaviors, while exercise intervention will play an effective role of alleviation.
Key words: sports physiology；restrained stress；exercise；social behavior；monoamine neurotransmitter；mouse |
