| （1.School of Physical Education，Shaanxi Normal University，Xian 710062，China；2.Canadian Centre for Behavioral Neuroscience，AB Lethbridge T1K3M4a，Canada) Abstract: From the perspective of competitive risks, in such 4 aspects as epidemiology, clinical manifestation, pathological analysis and neuroimaging science, the authors collated and reviewed researches in the area of sport related mild brain injury and chronic traumatic encephalopathy (CTE) that is closely related to it. There were the following main opinions: 1) among athletes there were quite a number of people who had an experience of sport related mild brain injury, the repeatability of such a type of injury tended to cause CTE; the suffered athletes were mostly in body contacting sports events such as boxing and football etc; 2) specific symptoms, such as brain weight loss, P-tau immune-positive neurofibrillary tangles, TDK-43 positive neurite, astrocytic hyperplasia, and such, were found in CTE pathological analysis; 3) sport related mild brain injury and CTE staging, classification and diagnosis standards had been put forward, but they still need to be supported by a lot of experiments; 4) in terms of neuroimaging science, mainly such techniques as DTI, fMRI and SWI were used to diagnose athlete patients; 5) current researches were mainly retrospective researches on athlete patients; related researches need to do more forward-looking work in order to make breakthroughs. To establish ideal animal models, to develop specific biomarkers, and such, are main ways to resolve current research bottleneck, and research on athlete CTE risk prevention should be strengthened.
Key words: sports medicine；nervous system；sport related mild brain injury；chronic traumatic encephalopathy；competitive risk；athlete |
